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ROS1-0219
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Histological diagnosis:

Right upper lobectomy specimen:1、(right upper lung) central type moderate to poorly differentiated adenocarcinoma of lung (solid type is about 40%, acinar type is about 60%), cancer tissue did not invade the pleura; 2. No cancer tissue is found in bronchial stump;3、 Metastatic carcinoma was found in (group 2 and 4) lymph nodes of (1 / 1), group 7 lymph nodes (2 / 2) and group 10 lymph nodes(2 / 2).

Immunohistochemistry:

CK7(+),CK18(+),TTF-1(+), SP-B(+), NapsinA(+), Ki-67(+,about 30%), P63(+),CK5/6(-),P40(-),Syn(-),CgA(-),CD56(-),Vimentin(-)

Gross examination findings:

Right upper lobectomy specimen:The volume is 12 * 7* 3cm. A central type tumor can be seen at 1.5cm away from the bronchial stump, part of the defect, and the remaining volume is 3.2*1.5*1cm.The section is gray yellow gray black and medium in quality.

Gender:M

Age:57

family history :Father died of cerebral infarction, mother alive

Serological examination :Serum CEA was normal

surgical mode :Right upper lobectomy

Tumor size:3.2*1.5*1cm

Disease status(primary/relapse):primary

G:II-III

TNM:T2aN2M0

Stage:IIIA

Gene:ROS1

Mutant Site:PCR

Mutation Type:fusion

% tumor :*

% necrosis:*

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