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ROS1-9737
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Histological diagnosis:

Right middle lobectomy specimen:1. (middle lobe of right lung) central type invasive adenocarcinoma, mainly solid, with tumor tissue invading pleura; 2. No cancer tissue found in bronchial stump; 3. metastatic carcinoma was found in hilar lymph node (1 / 1), (Group 12) lymph nodes (4 / 4), (group 1) lymph nodes (1 / 4), (Group 7) lymph nodes (8 / 10), (Group11) lymph nodes (1 / 3), (group4) lymph nodes(1 / 5) and (group 2) lymph nodes (4 / 5).

Immunohistochemistry:

CK7(++),TTF-1(++),NapsinA(++),Ki-67(+),CK5/6(-),P40(-),Syn(-),CgA(-),CD56(-),Vimentin(-),S-100(-),CD34(-).

Gross examination findings:

Right middle lobectomy specimen: A central tumor with a volume of 4 * 4 * 3cm can be seen at 2cm away from the bronchial stump, the section is grayish yellow and medium in quality.

Gender:M

Age:33

family history :Parents are alive

Serological examination :_

surgical mode :Right middle lobectomy

Tumor size: 4 * 4 * 3cm

Disease status(primary/relapse):primary

G:II-III

TNM:T2bN3M0

Stage:IIIB

Gene:ROS1

Mutant Site:PCR

Mutation Type:fusion

% tumor :*

% necrosis:*

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