Right middle lobectomy specimen：1. (middle lobe of right lung) central type mucinous / non mucinous mixed infiltrating adenocarcinoma with pleural invasion; 2. No cancer tissue was found in bronchial stump; 3. No metastasis carcinoma was found in hilar lymph node (0 / 1), para bronchial lymph node (0 / 1), (Group 3H) lymph node (0 / 2), (Group 10) lymph node (0 / 3), (Group 9) lymph node (0 / 1) and (Group 11) lymph node (0 / 2) .
1.TTF-1(+),SP-B(+),NapsinA(+),CK(+),CK7(+),CK18(+),Ki-67(+,about 35%),P63(+, a few cells),CK5/6(-),P40(-)，Syn(-),CgA(-),CD56(-),Vimentin(-),S-100(-),CD34(-)；2.PD-L1(SP263)(+，about 40%).
Right middle lobectomy specimen：A central type tumor can be seen at 3cm away from the bronchial stump, part of the defect, and the remaining volume is 5*3*2cm.The section is gray white and medium in quality.
Gender：F
Age：54
family history ：Parents are alive
Serological examination ：Serum CEA was normal
surgical mode ：Right middle lobectomy
Tumor size： 5*3*2cm
Disease status(primary/relapse)：primary
G：II
TNM：T3N0M0
Stage：IIB
Gene：ROS1
Mutant Site：PCR
Mutation Type：fusion
% tumor ：*
% necrosis：*
