Right lobectomy:( lower lobe of right lung) peripheral solid adenocarcinoma with necrosis,no tumor thrombus and nerve invasion in vessels, with pleural invasion.2. No cancer tissue is found in bronchial stump; 3、Metastasis carcinoma was found in hilar lymph nodes (2 / 3), 4、Adenocarcinoma was found in the right middle lung.
P40 (+, a few cell)、CK5/6(+)、CK7(+)、TTF(+)、NapsinA(-)、Ki-67(anout 40%).Histochemical staining：AB（There were scattered mucinous cells in the tumor）
Right lower and middle lobectomy: ( lower lobe of right lung) The volume is 13* 10* 3.5cm. A peripheral tumor can be seen at 3cm away from the bronchial stump with volume of 3.5*2.7*1.5cm.The section is gray yellow and medium in quality. ( middle lobe of right lung)The volume is 3.5* 2* 1.5cm. There is a gray yellow mass with volume of 1 * 1 * 0.5cm. The section is gray yellow and medium in quality.
Gender：F
Age：55
family history ：father died of lung cancer and mother is still alive
Serological examination ：Serum CEA , NSE was normal
surgical mode ：right lower lobectomy
Tumor size：3.5*2.7*1.5cm 1 * 1 * 0.5cm
Disease status(primary/relapse)：primary
G：III
TNM：T4N2M0
Stage：IIIB
Gene：ROS1
Mutant Site：PCR
Mutation Type：fusion
% tumor ：*
% necrosis：*
