Specimens for examination after operation:(left pleura)infiltrating malignant tumor was found in the fibrous connective tissue, and the histological characteristics suggested adenocarcinoma.Cancer was found in the lower lobe of left lung.
CK7(++),CK(++),TTF-1(++),SPB(++),NapsinA(++),ki-67(+,),CK5/6(-),P63(-),P40(-),Syn(-),CgA(-),CD56(-),Vimentin(-),WT-1(-).
The irregular tissue of gray red gray yellow was sent for examination with the total volume of 2 * 2 * 1cm, and the section is gray white and grayish yellow.In addition, a small amount of lower lobe of left lung tissue was seen, and a mass of 1.5 cm in diameter was found in it. The section is grayish white and medium in quality.
Gender：F
Age：44
family history ：Parents are alive
Serological examination ：Serum CEA was slightly higher and NSE was normal
surgical mode ：Left lower lobectomy
Tumor size：2*2*1cm 1.5*1.5*1.5c
Disease status(primary/relapse)：primary
G：II-III
TNM：T3N0M1a
Stage：IVA
Gene：ROS1
Mutant Site：PCR
Mutation Type：fusion
% tumor ：*
% necrosis：*
