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ROS1-2421
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Histological diagnosis:

Specimens for examination after operation:1. (lower lobe of right lung) peripheral invasive well differentiated adenocarcinoma, local acinar adenocarcinoma, local papillary adenocarcinoma, cancer tissue did not invade the pleura; 2, No cancer tissue was found in the bronchial stump; 3, No metastatic carcinoma was found in para bronchial lymph node (0 / 2), (Group 7) lymph node (0 / 1), (Group 10) lymph node (0 / 1), (Group 9) lymph node (0 / 2) and (Group 11) lymph node (0 / 1) .

Immunohistochemistry:

CK7(++),CK18(++),TTF-1(++),SPB(++), Ki-67(+),CK5/6(-),P40(-),Syn(-),CgA(-),CD56(-),Vimentin(-).

Gross examination findings:

The right lower lobectomy specimen was sent for examination with a volume of 14* 11 * 3.5cm. A piece of gray red lung tissue was sent for examination, with a volume of 4 * 2.7 * 0.8cm, and a gray yellow mass with partial defect can be seen in it, and the remaining volume is 3.2 * 1.7 * 0.4cm.

Gender:M

Age:63

family history :His father died of esophageal cancer 

Serological examination :Serum CEA was slightly higher and NSE was normal

surgical mode :right lower lobectomy

Tumor size:3.2*1.7*0.4cm

Disease status(primary/relapse):primary

G:I-II

TNM:T2aN0M0

Stage:IB

Gene:ROS1

Mutant Site:PCR

Mutation Type:fusion

% tumor :*

% necrosis:*

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