Right lower and middle lobectomy: (lower lobe of the right lung) peripheral invasive adenocarcinoma, mainly acinar, some mural adenocarcinoma, a small part of the region for micro papillary adenocarcinoma and solid adenocarcinoma with pleural invasion; no tumor thrombus and nerve invasion in vessels, 2. No cancer tissue is found in bronchial stump; 3、Metastasis carcinoma was found in hilar lymph nodes (2 / 3), (Group 12) lymph nodes (2 / 4), (group 1) lymph nodes (1 / 5), (Group 7) lymph nodes (2 / 6). No metastasis carcinoma was found in (Group11) lymph nodes (0 / 4), (group4) lymph nodes(0 /6) and (group 6) lymph nodes (0 / 5).4、(middle lobe of the right lung) Infiltrating adenocarcinoma was found in lung tissue.
CK7(++),EMA(++),ki-67(++,about 60%),SPB(+),TTF-1(+),CEA(+),CK5/6(+),NapsinA(+),Vimentin(-),P63(-),P40(-).
right lower and middle lobectomy: (lower lobe of the right lung )The volume is 11* 9* 3.5cm. A peripheral tumor can be seen at 2.5cm away from the bronchial stump with volume of 3.5*2.7*1.5cm.The section is gray yellow and medium in quality. (middle lobe of the right lung) Small pieces of lung tissue were sent for examination, with a volume of 5 * 4 *2.5. A gray white nodule was found in it with a volume of 2 * 1.5 * 1cm .The section is gray white and medium in quality.
Gender：M
Age：59
family history ：Parents are alive, A young sister has breast cancer
Serological examination ：Serum CEA , NSE was normal
surgical mode ：right lower and middle lobectomy
Tumor size：3.5*2.7*1.5cm 2 * 1.5 * 1cm
Disease status(primary/relapse)：primary
G：II-III
TNM：T4N3M0
Stage：IIIC
Gene：ROS1
Mutant Site：PCR
Mutation Type：fusion
% tumor ：*
% necrosis：*
