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ROS1-3182
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Histological diagnosis:

(lower lobe of the left lung) invasive adenocarcinoma, some papillary, part acinar, the cancer tissue is invasion of the pleura.

Immunohistochemistry:

CK7(++),TTF-1(++),NapsinA(++),ki-67(+,about 6%),SPB(+),CK5/6(-),P63(-),P40(-),Syn(-),CgA(-),CD56(-),Vimentin(-),S-100(-),CD34(-).

Gross examination findings:

Left lower lobectomy specimen:The volume is 9 * 4 * 2.5cm. There is a gray yellow gray red mass, part of the defect, and the remaining volume is 4.5 * 4.5 * 1.5cm.The section is gray red gray yellow and medium in quality.

Gender:M

Age:84

family history :Parents died for unknown reasons

Serological examination :Serum CEA , NSE was normal

surgical mode :Left lower lobectomy

Tumor size: 4.5 * 4.5 * 1.5cm

Disease status(primary/relapse):primary

G:II

TNM:T3N0M0

Stage:IIB

Gene:ROS1

Mutant Site:PCR

Mutation Type:fusion

% tumor :*

% necrosis:*

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