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ROS1-298
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Histological diagnosis:

Right lobectomy:( lower lobe of right lung) peripheral solid adenocarcinoma with necrosis,no tumor thrombus and nerve invasion in vessels, with pleural invasion.2. No cancer tissue is found in bronchial stump; 3、Metastasis carcinoma was found in hilar lymph nodes (2 / 3), 4、Adenocarcinoma was found in the right middle lung.

Immunohistochemistry:

P40 (+, a few cell)、CK5/6(+)、CK7(+)、TTF(+)、NapsinA(-)、Ki-67(anout 40%).Histochemical staining:AB(There were scattered mucinous cells in the tumor)

Gross examination findings:

Right lower and middle lobectomy: ( lower lobe of right lung) The volume is 13* 10* 3.5cm. A peripheral tumor can be seen at 3cm away from the bronchial stump with volume of 3.5*2.7*1.5cm.The section is gray yellow and medium in quality. ( middle lobe of right lung)The volume is 3.5* 2* 1.5cm. There is a gray yellow mass with volume of 1 * 1 * 0.5cm. The section is gray yellow and medium in quality.

Gender:F

Age:55

family history :-

Serological examination :-

surgical mode :-

Tumor size:3.5*2.7*1.5cm 1 * 1 * 0.5cm

Disease status(primary/relapse):primary

G:III

TNM:T4N2M0

Stage:IIIB

Gene:ROS1

Mutant Site:

Mutation Type:Fusioin

% tumor :-

% necrosis:-

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